abstract：UNLABELLED:Retinal pigment epithelium (RPE) builds the outer blood-retinal barrier of the eye and plays an important role in pathogenesis of the sight threatening disease equine recurrent uveitis (ERU). ERU is a spontaneous autoimmune mediated inflammatory disease characterised by the breakdown of the outer blood-retin...

journal_title：Journal of proteomics

authors： Uhl PB,Szober CM,Amann B,Alge-Priglinger C,Ueffing M,Hauck SM,Deeg CA

更新日期：2014-09-23 00:00:00

abstract：UNLABELLED:The endocrine role of adipose tissue and its involvement in several physiological and pathological processes are well recognized. Studies on human, mouse and rat adipose tissues have made clear that subcutaneous and visceral deposits play different roles, which is also reflected by different protein and gene...

journal_title：Journal of proteomics

authors： Restelli L,Codrea MC,Savoini G,Ceciliani F,Bendixen E

更新日期：2014-08-28 00:00:00

abstract：UNLABELLED:This study was conducted to define differences in Fusarium oxysporum f. sp. fragariae (Fof) isolates with different virulence efficiency to strawberry at the proteome level, in combination with their differences in mycelial growth, conidial production and germination. Comparative proteome analyses revealed s...

journal_title：Journal of proteomics

authors： Fang X,Barbetti MJ

更新日期：2014-08-28 00:00:00

abstract：UNLABELLED:Altered glycosylation is commonly observed in colorectal cancer. In vitro models are frequently used to study this cancer but little is known about the differences that may exist between these model cell systems and tumour tissue. We have compared the membrane protein glycosylation of five colorectal cancer ...

journal_title：Journal of proteomics

authors： Chik JH,Zhou J,Moh ES,Christopherson R,Clarke SJ,Molloy MP,Packer NH

更新日期：2014-08-28 00:00:00

abstract：UNLABELLED:Plant receptor-like kinases (RLKs) constitute a large family of receptors coordinating developmental programs with adaptation to environmental stresses including immune defenses. BRI1-ASSOCIATED KINASE 1 (BAK1), a member of the plant RLK family, forms receptor complexes with multiple RLK proteins including B...

journal_title：Journal of proteomics

authors： Wang Y,Li Z,Liu D,Xu J,Wei X,Yan L,Yang C,Lou Z,Shui W

更新日期：2014-08-28 00:00:00

abstract：:Intensive methodological developments and technology innovation have been devoted to protein-protein interaction studies over 20years. Genetic indirect assays and sophisticated large scale biochemical analyses have jointly contributed to the elucidation of protein-protein interactions, still with a lot of drawbacks de...

journal_title：Journal of proteomics

authors： Legrain P,Rain JC

更新日期：2014-07-31 00:00:00

abstract：UNLABELLED:Extracellular vesicles are produced by many pathogenic microorganisms and have varied functions that include secretion and release of microbial factors, which contribute to virulence. Very little is known about vesicle production by Gram-positive bacteria, as well as their biogenesis and release mechanisms. ...

journal_title：Journal of proteomics

authors： Olaya-Abril A,Prados-Rosales R,McConnell MJ,Martín-Peña R,González-Reyes JA,Jiménez-Munguía I,Gómez-Gascón L,Fernández J,Luque-García JL,García-Lidón C,Estévez H,Pachón J,Obando I,Casadevall A,Pirofski LA,Rodríguez-Ortega M

更新日期：2014-06-25 00:00:00

abstract：UNLABELLED:Dietary fiber/starch imbalance can lead to diarrhea in rabbits. However, the underlying molecular mechanisms are largely unknown, and this is the first study on the proteome profile of the cecal tissue of diarrheic rabbits. In this study, one group of weanling rabbits was fed a high fiber/starch diet (contro...

journal_title：Journal of proteomics

authors： Zhu Y,Wang C,Wang X,Li B,Li F

更新日期：2014-05-30 00:00:00

abstract：:Mass spectrometry imaging (MSI) is of high and growing interest in life science research, but the investment for necessary equipment is often prohibitive for small research groups. Therefore, we developed a basic MSI system from low cost 'Plug and Play' components, which are connected to the Universal Serial Bus (USB)...

journal_title：Journal of proteomics

authors： Maldonado-Torres M,López-Hernández JF,Jiménez-Sandoval P,Winkler R

更新日期：2014-05-06 00:00:00

abstract：UNLABELLED:Haptoglobin (Hp) and immunoglobulins are plasma glycoproteins involved in the immune reaction of the organism after infection and/or inflammation. Porcine circovirus type 2-systemic disease (PCV2-SD), formerly known as postweaning multisystemic wasting syndrome (PMWS), is a globally spread pig disease of gre...

journal_title：Journal of proteomics

authors： Marco-Ramell A,Miller I,Nöbauer K,Möginger U,Segalés J,Razzazi-Fazeli E,Kolarich D,Bassols A

更新日期：2014-04-14 00:00:00

abstract：UNLABELLED:Clostridial collagenases are among the most efficient degraders of collagen. Most clostridia are saprophytes and secrete proteases to utilize proteins in their environment as carbon sources; during anaerobic infections, collagenases play a crucial role in host colonization. Several medical and biotechnologic...

journal_title：Journal of proteomics

authors： Eckhard U,Huesgen PF,Brandstetter H,Overall CM

更新日期：2014-04-04 00:00:00

abstract：UNLABELLED:The molecular pathways that trigger the amazing intrinsic regenerative ability of echinoderm nervous system are still unknown. In order to approach this subject, a 2D-DIGE proteomic strategy was used, to screen proteome changes during neuronal regeneration in vivo, using starfish (Asteroidea, Echinodermata) ...

journal_title：Journal of proteomics

authors： Ferraz Franco C,Santos R,Varela Coelho A

更新日期：2014-03-17 00:00:00

abstract：UNLABELLED:Alterations in the sera proteins between patients with Primary Open-Angle Glaucoma (POAG), Pseudoexfoliation Glaucoma (PEXG), and healthy controls were identified through a proven approach utilizing equalization of high-abundance serum proteins with ProteoMiner™, two-dimensional fluorescent difference gel el...

journal_title：Journal of proteomics

authors： González-Iglesias H,Álvarez L,García M,Escribano J,Rodríguez-Calvo PP,Fernández-Vega L,Coca-Prados M

更新日期：2014-02-26 00:00:00

abstract：UNLABELLED:Schistosomiasis remains one of the major neglected tropical diseases (NTDs) causing morbidity of humans residing in the tropical countries. Much effort has been devoted to the development of vaccines, since it is recognized that vaccines can be served as an important supplementary component alongside chemoth...

journal_title：Journal of proteomics

authors： Chen JH,Zhang T,Ju C,Xu B,Lu Y,Mo XJ,Chen SB,Fan YT,Hu W,Zhou XN

更新日期：2014-02-26 00:00:00

abstract：UNLABELLED:Downy mildew is a serious fungal disease in non-heading Chinese cabbage (Brassica campestris ssp. chinensis Makino) that is caused by Hyaloperonospora parasitica, which infects members of the Brassicaceae family. For breeding improvement, researchers must understand the defence mechanisms employed by non-hea...

journal_title：Journal of proteomics

authors： Sun C,Wang L,Hu D,Riquicho AR,Liu T,Hou X,Li Y

更新日期：2014-02-26 00:00:00

abstract：UNLABELLED:Secretion of bioactive mediators regulates cell interactions with the microenvironment in tissue homeostasis and wound healing processes. We assessed the cardiomyocyte secretory response to hypoxia with the aim of identifying key mediators of tissue pathology and repair after ischemic heart attack. We profil...

journal_title：Journal of proteomics

authors： Li X,Ren Y,Sorokin V,Poh KK,Ho HH,Lee CN,de Kleijn D,Lim SK,Tam JP,Sze SK

更新日期：2014-02-26 00:00:00

abstract：UNLABELLED:Pathogenicity of the rice pathogenic bacterium Xanthomonas oryzae pv. oryzae depends on a Hrp (hypersensitive response and pathogenicity) type III secretion system; the expression of which is induced in planta. Expression of the hrp operons is under transcriptional control of two key regulatory proteins, Hrp...

journal_title：Journal of proteomics

authors： Robin GP,Ortiz E,Szurek B,Brizard JP,Koebnik R

更新日期：2014-01-31 00:00:00

abstract：:Ever since antibiotics were used to help humanity battle infectious diseases, microorganisms straight away fought back. Antibiotic resistance mechanisms indeed provide microbes with possibilities to by-pass and survive the action of antibiotic drugs. Several methods have been employed to identify these microbial resis...

journal_title：Journal of proteomics

authors： Vranakis I,Goniotakis I,Psaroulaki A,Sandalakis V,Tselentis Y,Gevaert K,Tsiotis G

更新日期：2014-01-31 00:00:00

abstract：UNLABELLED:The kinetoplastid protozoan parasite, Leishmania donovani, is the causative agent of kala azar or visceral leishmaniasis. Kala azar is a severe form of leishmaniasis that is fatal in the majority of untreated cases. Studies on proteomic analysis of L. donovani thus far have been carried out using homology-ba...

journal_title：Journal of proteomics

authors： Nirujogi RS,Pawar H,Renuse S,Kumar P,Chavan S,Sathe G,Sharma J,Khobragade S,Pande J,Modak B,Prasad TS,Harsha HC,Patole MS,Pandey A

更新日期：2014-01-31 00:00:00

abstract：UNLABELLED:The proteome of the venom of Naja haje legionis, the only medically important elapid species in Morocco, has been elucidated by using a combination of proteomic techniques that includes size exclusion chromatography, reverse-phase HPLC, Tricine/SDS-Page, tryptic digestion, Q-TOF tandem mass spectrometry and ...

journal_title：Journal of proteomics

authors： Malih I,Ahmad rusmili MR,Tee TY,Saile R,Ghalim N,Othman I

更新日期：2014-01-16 00:00:00

abstract：UNLABELLED:This study aimed at investigating the proteomic adaptation of Lactobacillus plantarum strains. Cultivation of L. plantarum strains under food-like conditions (wheat flour hydrolyzed, whey milk, tomato juice) affected some metabolic traits (e.g., consumption of carbohydrates and synthesis of organic acids) co...

journal_title：Journal of proteomics

authors： Siragusa S,De Angelis M,Calasso M,Campanella D,Minervini F,Di Cagno R,Gobbetti M

更新日期：2014-01-16 00:00:00

abstract：UNLABELLED:There exists a growing demand in the proteomics community to standardize experimental methods and liquid chromatography-mass spectrometry (LC/MS) platforms in order to enable the acquisition of more precise and accurate quantitative data. This necessity is heightened by the evolving trend of verifying and va...

journal_title：Journal of proteomics

authors： Percy AJ,Chambers AG,Yang J,Jackson AM,Domanski D,Burkhart J,Sickmann A,Borchers CH

更新日期：2013-12-16 00:00:00

abstract：UNLABELLED:Mass spectrometry is already a well-established protein identification tool and recent methodological and technological developments have also made possible the extraction of quantitative data of protein abundance in large-scale studies. Several strategies for absolute and relative quantitative proteomics an...

journal_title：Journal of proteomics

authors： Martínez-Bartolomé S,Deutsch EW,Binz PA,Jones AR,Eisenacher M,Mayer G,Campos A,Canals F,Bech-Serra JJ,Carrascal M,Gay M,Paradela A,Navajas R,Marcilla M,Hernáez ML,Gutiérrez-Blázquez MD,Velarde LF,Aloria K,Beaskoetxea

更新日期：2013-12-16 00:00:00

abstract：UNLABELLED:Despite the noxious effects inflicted by Dinoponera ant's envenomation, the information about the biological properties and composition of their venom is still very limited. Ants from the genus Dinoponera are believed to be the world's largest living ants with a body length of 3cm. Their occurrence is restri...

journal_title：Journal of proteomics

authors： Cologna CT,Cardoso Jdos S,Jourdan E,Degueldre M,Upert G,Gilles N,Uetanabaro AP,Costa Neto EM,Thonart P,de Pauw E,Quinton L

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:Accurate biomarker quantification requires carefully chosen normalisation procedures. When single proteins are used as loading controls (LCs), it is crucial that their expressional stability must be known. Platelets are an important biomarker source, especially for neurological diseases. We performed a syste...

journal_title：Journal of proteomics

authors： Baumgartner R,Umlauf E,Veitinger M,Guterres S,Rappold E,Babeluk R,Mitulović G,Oehler R,Zellner M

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:This study constitutes the first attempt to understand at the proteomic level the fungal response to ionic liquid stress. Ascomycota are able to grow in media supplemented with high concentrations of an ionic liquid, which, in turn, lead to major alterations in the fungal metabolic footprint. Herein, we anal...

journal_title：Journal of proteomics

authors： Martins I,Hartmann DO,Alves PC,Planchon S,Renaut J,Leitão MC,Rebelo LP,Silva Pereira C

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:Hg discharged into the environmental waters can generally be bioaccumulated, transformed and transmited by living organisms, thus resulting in the formation of Hg-toxicity food chains. The pathway and toxicology of food chain contaminated with environmental Hg are rarely revealed by proteomics. Here, we show...

journal_title：Journal of proteomics

authors： Zhang QH,Huang L,Zhang Y,Ke CH,Huang HQ

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:The need for biomarkers that illuminate the pathophysiology of type 1 diabetes (T1D), enhance early diagnosis and provide additional avenues for therapeutic intervention is well recognized in the scientific community. We conducted a proteome-scale, two-stage serological AAb screening followed by an independe...

journal_title：Journal of proteomics

authors： Miersch S,Bian X,Wallstrom G,Sibani S,Logvinenko T,Wasserfall CH,Schatz D,Atkinson M,Qiu J,LaBaer J

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:Milk and dairy products are central elements in the human diet. It is estimated that 108kg of milk per year are consumed per person worldwide. Therefore, dairy production represents a relevant fraction of the economies of many countries, being cattle, sheep, goat, water buffalo, and other ruminants the main ...

journal_title：Journal of proteomics

authors： Ferreira AM,Bislev SL,Bendixen E,Almeida AM

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:Despite being ischemic stroke a leading cause of death and functional disability, there are no other accurate tools to predict outcome of patients beyond clinical variables such as age and stroke severity. In this scenario, defining protein changes associated with acute ischemic brain damage might help to id...

journal_title：Journal of proteomics

authors： García-Berrocoso T,Penalba A,Boada C,Giralt D,Cuadrado E,Colomé N,Dayon L,Canals F,Sanchez JC,Rosell A,Montaner J

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:Mitral regurgitation (MR) is a common valvular lesion frequently caused by mitral valve prolapse (MVP). Surgical intervention in MVP patients with significant MR is predicated on symptoms and measures of left ventricular dysfunction. Because these indicators may be subjective or imprecise, serological biomar...

journal_title：Journal of proteomics

authors： Tan HT,Ling LH,Dolor-Torres MC,Yip JW,Richards AM,Chung MC

更新日期：2013-12-06 00:00:00

abstract：UNLABELLED:Quercus suber L. is a forest tree with remarkable ecological, social and economic value in the southern Europe ecosystems. To circumvent the difficulties of breeding such long-lived species like Q. suber in a conventional fashion, clonal propagation of Q. suber elite trees can be carried out, although this p...

journal_title：Journal of proteomics

authors： Gomez-Garay A,Lopez JA,Camafeita E,Bueno MA,Pintos B

更新日期：2013-11-20 00:00:00

abstract：UNLABELLED:Oleaginous microalgae are capable of producing large quantities of fatty acids and triacylglycerides. As such, they are promising feedstocks for the production of biofuels and bioproducts. Genetic strain-engineering strategies offer a means to accelerate the commercialization of algal biofuels by improving t...

journal_title：Journal of proteomics

authors： Guarnieri MT,Nag A,Yang S,Pienkos PT

更新日期：2013-11-20 00:00:00

abstract：UNLABELLED:The genus Mentha has been widely used in food, flavor, culinary, cosmetic and pharmaceutical industries. Substantial damage to this crop happened regularly due to environmental stresses like metal toxicity and pathogen attack. Here, an approach has been taken to raise transgenic mint over-expressing γ-glutam...

journal_title：Journal of proteomics

authors： Sinha R,Bhattacharyya D,Majumdar AB,Datta R,Hazra S,Chattopadhyay S

更新日期：2013-11-20 00:00:00

abstract：:Plant growth and productivity are adversely influenced by various environmental stresses, which often lead to reduced seedling growth and decreased crop yields. Plants respond to stressful conditions through changes in 'omics' profiles, including transcriptomics, proteomics, and metabolomics. Linking plant phenotype t...

journal_title：Journal of proteomics

authors： Komatsu S,Shirasaka N,Sakata K

更新日期：2013-11-20 00:00:00

abstract：UNLABELLED:Heterosis is the superior performance of heterozygous F1-hybrid plants compared to their homozygous genetically distinct parents. Seminal roots are embryonic roots that play an important role during early maize (Zea mays L.) seedling development. In the present study the most abundant soluble proteins of 2-4...

journal_title：Journal of proteomics

authors： Marcon C,Lamkemeyer T,Malik WA,Ungrue D,Piepho HP,Hochholdinger F

更新日期：2013-11-20 00:00:00

abstract：:Molecular aging of proteins results from the complex association of different reactions that lead to the progressive alteration of their structural and functional properties. These reactions, which include oxidation, glycoxidation, carbonylation and carbamylation, occur during aging and are amplified in various chroni...

journal_title：Journal of proteomics

authors： Gillery P,Jaisson S

更新日期：2013-10-30 00:00:00

abstract：UNLABELLED:The methylotrophic yeast Pichia pastoris is an attractive platform for a plethora of recombinant proteins. There is growing evidence that host cells producing recombinant proteins are exposed to a variety of cellular stresses resulting in the induction of the unfolded protein response (UPR) pathway. At prese...

journal_title：Journal of proteomics

authors： Lin XQ,Liang SL,Han SY,Zheng SP,Ye YR,Lin Y

更新日期：2013-10-08 00:00:00

abstract：UNLABELLED:We attempted to identify biomarkers that would predict responsiveness of osteosarcoma (OS) to induction chemotherapy. Tumor tissues obtained by open biopsy before induction chemotherapy were investigated. On the basis of histological observations at the time of surgery and the Huvos grading system, 7 patient...

journal_title：Journal of proteomics

authors： Kubota D,Mukaihara K,Yoshida A,Tsuda H,Kawai A,Kondo T

更新日期：2013-10-08 00:00:00

abstract：UNLABELLED:Dental cementum (DC) is a bone-like tissue covering the tooth root and responsible for attaching the tooth to the alveolar bone (AB) via the periodontal ligament (PDL). Studies have unsuccessfully tried to identify factors specific to DC versus AB, in an effort to better understand DC development and regener...

journal_title：Journal of proteomics

authors： Salmon CR,Tomazela DM,Ruiz KG,Foster BL,Paes Leme AF,Sallum EA,Somerman MJ,Nociti FH Jr

更新日期：2013-10-08 00:00:00